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Table 2 Univariable and multivariable cox regression analysis of MIR31HG and its splice variants with clinicopathological features in the Mannheim cohort (HR hazard ratio, CI confidence interval, LVI lymphovascular invasion, Basal high KRT5 expression, Non-basal low KRT5 expression, significant p values are bold)

From: Long noncoding RNA MIR31HG and its splice variants regulate proliferation and migration: prognostic implications for muscle invasive bladder cancer

Factor Univariable Multivariable
HR (95% CI) p HR (95%CI) p
Diagnosis Age
 <70 vs. ≥70 0.701(0.406–1.212) 0.2041
Gender
 Male vs. Female 0.980(0.535–1.795) 0.9485
Stage
 T2 vs. T3/4 0.401(0.202–0.797) 0.0092 0.445(0.220–0.900) 0.0243
LVI
 Negative vs. Positive 0.550(0.075–4.050) 0.5570
Lymphnode Status
 Negative vs. Positive 0.547(0.245–1.221) 0.1418 0.694(0.243–1.987) 0.4961
Molecular Subtype
 Basal vs. Non-basal 1.202(0.596–2.422) 0.6073
MIR31HG
 Low vs. High 1.720(0.681–4.347) 0.2522
MIR31HGΔE1
 Low vs. High 3.753(1.457–9.664) 0.0063 1.896(0.831–4.329) 0.1294
MIR31HGΔE3
 Low vs. High 2.522(1.235–5.149) 0.0114 2.805(1.293–6.083) 0.0090