Fig. 6

Verification of HBV infection associated with the development of HCC. a The proliferation of Huh7 cells transfected with pHBV1.3 (left) or not (right) with miRNA-30b-5p inhibition, MINPP1 knockdown and control was determined using the CCK-8 assay. b Scrape motility were measured by cell migration assays at 0, 24, and 48 h in Huh7 cells transfected with pHBV1.3 (upper) or not (down) with miRNA-30b-5p inhibition, MINPP1 knockdown and control. The wound healing rate was tested by Image J software. c Cellular glucose (upper), lactate (middle), and 2-PG (down) levels in Huh7 cells transfected with pHBV1.3 with miRNA-30b-5p inhibition, MINPP1 knockdown and control. d Cellular glucose (upper), lactate (middle), and 2--PG (down) levels were measured in the Huh7 cells transfected with inhibitor of miRNA-30b-5p, MINPP1 knockdown, and control construct. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001, ^****P < 0.0001, NS: no statistics