Fig. 4

Protein levels of PER3, GLS2, CREM and TXNIP in AT1 prostate and Walker-256 mammary carcinoma tumors in vivo 24 h after (a) inducing metabolic acidosis by forcing glycolytic metabolism or (b) intratumoral injection of lactic acid. n = 4–18; (*) p < 0.05, (**) p < 0.01 vs. control; (^#) p < 0.05, (^##) p < 0.01 AT1 vs. Walker-256 cells