Fig. 4

Fibroblasts with high expression of YAP1 promote tumour growth in vivo. a Tumour photos taken with a digital camera. b Statistical table of the number of tumours in each experimental group. c The line graph shows the subcutaneous tumour volumes as a function of time. The data were recorded from the second week to the fifth week (* P < 0.05). e Western blot was used to detect the expression levels of YAP1, SRC, α-SMA and Ki67 in tumour tissues. GAPDH was used as an endogenous reference gene. f Immunohistochemical staining was used to detect the expression levels and positions of YAP1, SRC, α-SMA, Ki67 and MMP2 in tumour tissues. The tumour cells and stromal cells were separated by curves. T: tumour cells, S: stromal cells