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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Neuropilin 1 and Neuropilin 2 gene invalidation or pharmacological inhibition reveals their relevance for the treatment of metastatic renal cell carcinoma

Fig. 7

NRPa-308 inhibits 786-O cell migration velocity more efficiently than sunitinib. a Photographs of scratch assay on cell monolayers in different experimental conditions; untreated, treated by NRPa-308 and by sunitinib. b The effects of NRPa-308 and sunitinib on 786-O cell migration at different concentrations by quantifying the above-mentioned experiments. c NRPa-308 (2 μM) inhibited the invasion of collagen-coated Boyden chambers (Control (Ctrl) and NRPa-308-treated duplicates are shown). d Quantification of the results shown in (c). **p < 0.01; *** p < 0.001

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