Fig. 8From: Neuropilin 1 and Neuropilin 2 gene invalidation or pharmacological inhibition reveals their relevance for the treatment of metastatic renal cell carcinomaHigh NRPa-308 concentration stimulates the production of NRPs ligands and of pro-angiogenic/pro-inflammatory cytokines. The effects of NRPa-308 and sunitinib on the production of different cytokines were evaluated by ELISA; a VEGFA, b VEGFC, production (c) CXCL8, d CXCL5. *p < 0.05; **p < 0.01; *** p < 0.001Back to article page