Fig. 4

MiR-622 inhibits the malignancy of UM cells and reverses the promoting effects of circ_0119872. a The levels of miR-622 in OCM-1A and MUM-2B cells transfected with miR-622 mimics and the corresponding negative controls were detected by qRT-PCR. b and c CCK-8 and EdU assays demonstrate that circ_0119872 increases the proliferation of OCM-1A and MUM-2B cells, and when co-transfected with miR-622, the promoting effect is reversed. d HUVEC tube formation assay demonstrates that circ_0119872 increases the angiogenesis of OCM-1A and MUM-2B cells, and when co-transfected with miR-622, the promoting effect is reversed. Data are represented as the mean ± SD of three independent experiments (* P < 0.05)