Fig. 8

HOXA10-induced HDAC1 enhanced the tumorigenesis of LAD cells via DNMT1/KLF4. a The macroscopic appearance of the xenograft tumor implanted subcutaneously in mice. b The growth curve of the tumor volume in each group was graphed. c The tumor weight among the groups was compared. d Immunohistochemical detection of HOXA10, HDAC1, DNMT1, and KLF4 proteins in tumor tissue sections was performed (200 ×). e Western blot analysis of HOXA10, HDAC1, DNMT1, and KLF4 protein expression was performed (normalized to GAPDH). All experiments were done in triplicate. * p < 0.05