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Table 2 Univariate and Multivariate analysis according to cancer status in Validation1 and 2 cohorts

From: A preliminary study of micro-RNAs as minimally invasive biomarkers for the diagnosis of prostate cancer patients

 

Validation cohort 1

Validation cohort 2

Variables

Univariate

 

Multivariate

 

Univariate

 

Multivariate

 
 

Odds ratio (CI)

p

Odds ratio (CI)

p

Odds ratio (CI)

p

Odds ratio (CI)

p

AGE

1.06(1.00–1.11)

.036

1.04(0.93–1.17)

.47

1.05(.99–1.11)

.68

  

PSA

.97(0.87–1.07)

.54

  

1.05(1.00–1.11)

.52

  

miR-26b-5p

.0001(.00–.002)

.0001

.0001(.00–.48)

.0001

.11(.001–.109)

<.0001

.011(.001–.11)

.0001

miR-30c

.98(0.95–1.01)

.14

  

.984(.96–1.101)

.27

  

miR-21-5p

.99(0.99–1.00)

.21

  

.99(.99–1.00)

.29

  

miR-98-5p

.77(0.54–1.10)

.160

  

.68(.43–1.09)

.11

  

miR-4732-3p

6.60(2.46–17.37)

.0001

1.82(.55–6.04)

.33

1.53(1.01–2.33)

.04

.98(0.59–1.69)

.94

Let7a-5p

.99(.98–1.00)

.117

  

.99(.97–1.00)

.16

  
  1. Abbreviations CI, Confident Interval, p p value, PSA Prostate Specific Antigen. Data are presented as odds ratio (CI). Empty cells correspond to variables that were not measured. Baseline variables that achieved a level of significance of p < .05 in the univariate analysis were entered into multivariate models
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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