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Table 2 Univariate and Multivariate analysis according to cancer status in Validation1 and 2 cohorts

From: A preliminary study of micro-RNAs as minimally invasive biomarkers for the diagnosis of prostate cancer patients

  Validation cohort 1 Validation cohort 2
Variables Univariate   Multivariate   Univariate   Multivariate  
  Odds ratio (CI) p Odds ratio (CI) p Odds ratio (CI) p Odds ratio (CI) p
AGE 1.06(1.00–1.11) .036 1.04(0.93–1.17) .47 1.05(.99–1.11) .68   
PSA .97(0.87–1.07) .54    1.05(1.00–1.11) .52   
miR-26b-5p .0001(.00–.002) .0001 .0001(.00–.48) .0001 .11(.001–.109) <.0001 .011(.001–.11) .0001
miR-30c .98(0.95–1.01) .14    .984(.96–1.101) .27   
miR-21-5p .99(0.99–1.00) .21    .99(.99–1.00) .29   
miR-98-5p .77(0.54–1.10) .160    .68(.43–1.09) .11   
miR-4732-3p 6.60(2.46–17.37) .0001 1.82(.55–6.04) .33 1.53(1.01–2.33) .04 .98(0.59–1.69) .94
Let7a-5p .99(.98–1.00) .117    .99(.97–1.00) .16   
  1. Abbreviations CI, Confident Interval, p p value, PSA Prostate Specific Antigen. Data are presented as odds ratio (CI). Empty cells correspond to variables that were not measured. Baseline variables that achieved a level of significance of p < .05 in the univariate analysis were entered into multivariate models