Fig. 2
From: METTL3-mediated m6A mRNA modification of FBXW7 suppresses lung adenocarcinoma
Correlation between METTL3 downregulation and unfavorable prognosis in patients with lung adenocarcinoma (LUAD). a Relative METTL3 protein levels in paired tissues from eight patients with LUAD. b Western blotting of Mcl-1, c-Myc, cleaved caspase 3, Bax, METTL3, and FBXW7 protein expression in HCC827 cells with METTL3 overexpression or depletion. c–d METTL3 overexpression or depletion affected HCC827 cell apoptosis and proliferation. e Representative immunohistochemical staining for METTL3 in LUAD and paired normal tissues from one patient. Bar = mean ± SD. *p < 0.05