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Table 2 Cohort characteristics of esophageal cancer patients

From: Cirsiliol targets tyrosine kinase 2 to inhibit esophageal squamous cell carcinoma growth in vitro and in vivo

Clinicopathological characteristics

TYK2 protein expression level

Low (n = 45)

High (n = 46)

P

Gender

 Male

29 (64.4%)

39 (84.8%)

0.113

 Female

16 (35.6%)

7 (15.2%)

 

Age

 ≤ 60

14 (31.1%)

17 (37.0%)

0.761

 > 60

31 (68.9%)

29 (63.0%)

 

Tumor size

 ≤ 5 cm

31 (68.9%)

25 (54.3%)

0.528

 > 5 cm

14 (31.1%)

21 (45.7%)

 

Histological grade

 Well/moderately

30 (66.7%)

37 (80.4%)

0.355

 Poorly

15 (33.3%)

9 (19.6%)

 

T classification

 T1

4 (8.9%)

2 (4.3%)

0.543

 T2

7 (15.6%)

5 (10.9%)

 

 T3

32 (71.1%)

38 (82.6%)

 

 T4

2 (4.4%)

1 (2.2%)

 

N classification

 N0

22 (48.9%)

19 (41.3%)

0.448

 N1

16 (35.6%)

14 (30.4%)

 

 N2

6 (13.3%)

10 (21.8%)

 

 N3

1 (2.2%)

3 (6.5%)

 

Clinical stage

 1

5 (11.1%)

2 (4.4%)

0.033

 2

20 (44.5%)

19 (41.3%)

 

 3

18 (40.0%)

21 (45.6%)

 

 4

2 (4.4%)

4 (8.7%)

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