Fig. 2
From: ROC1 promotes the malignant progression of bladder cancer by regulating p-IκBα/NF-κB signaling
ROC1 promoted the migration and invasion of BCa cell lines. a, b Wound-healing assays showing that ROC1 overexpression promoted the migration of T24 and 5637 cells, and that ROC1 knockdown showed the opposite effects. The values are expressed as the mean ± standard deviation (SD) of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001, two-tailed Student’s t-test. c, d Representative images and summary of Transwell-invasion assay data showing that ROC1 overexpression promoted T24 and 5637 cell invasion, whereas ROC1 knockdown showed the opposite effect. Scale bar, 100 μm. The values are expressed as the mean ± SD of three independent experiments. **P < 0.01, ***P < 0.001, two-tailed Student’s t-test