Fig. 8

Chemotherapy exerts different effects on CDA expression in patient tumor tissues. a: Comparison of CDA expression between patient tumor tissue resected after neoadjuvant chemotherapy and primary resected tumors, Independent-samples Mann-Whitney U test, Wilcoxon W: 1516, Asymptotic sig. (2-sided test: 0.780); b: Samples with marked decrease of CDA expression after neoadjuvant chemotherapy, both preneoadjuvant specimen are lymph node biopsies. Patient 1 H-Score preneoadjuvant of 9 and postneoadjuvant of 1, Patient 2 H-Score preneoadjuvant of 9 and postneoadjuvant of 4; c: Samples with marked increase of CDA expression after neoadjuvant chemotherapy. Patient 1 H-Score preneoadjuvant of 1 and postneoadjuvant of 9, Patient 2 H-Score preneoadjuvant of 0 and postneoadjuvant of 9, Patient 3 H-Score preneoadjuvant of 2 and postneoadjuvant of 4