Fig. 7

Exosomal circ_0072083 from resistant cells increases sensitive glioma cell growth in a xenograft model under TMZ. U251 cells were used to establish the xenograft model, and then mice were treated via exosome from U251/TR cells with transfection of sh-circ_0072083 or sh-NC and TMZ (n = 5). a and b Tumor volume and wight were detected in each group. c and d circ_0072083, miR-1252-5p, ALKBH5 and NANOG levels were examined in tumor tissues of each group. ^*P < 0.05