Fig. 5
From: Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression
Heat map and clustering of gene expression data for PaCa 5061 and BxPC3 xenograft tumors: TGF-β signaling (a), epithelial-mesenchymal transition (b) and immune status (c). A significantly higher expression is shown in red and a lower expression in green. In contrast to the gene expression changes in BxPC3 xenograft tumors (no canonical signaling due to the deletion of SMAD4), changes in PaCa 5061 (SMAD4 intact) xenograft tumors appeared organized