Fig. 1

miR-455-5p was reduced in MTC and overexpression of miR-455-5p suppressed MTC cell proliferation, migration, and invasion. a Relative miR-455-5p levels in MTC tissues and adjacent non-tumor tissues. b Survival rate in patients with high miR-455-5p level and low miR-455-5p level. c Relative miR-455-5p levels in MTC cells. d Relative miR-455-5p levels in MTC cells transfected with mimics NC or miR-455-5p mimics. e & f Representative images of colonies formed in mimics NC transfected or miR-455-5p mimics transfected MTC cells. g Flow cytometry analysis of the number of transfected cells in G1, S, and G2 phases. h Flow cytometry analysis of cell apoptosis in MTC cells transfected with mimics NC or miR-455-5p mimics. i & j Transwell assay to quantify the migration and invasion abilities of transfected cells. k & l EMT-related protein levels in transfected MTC cells. * P < 0.05; ** P < 0.01; *** P < 0.001