Fig. 6

circPVT1 regulated MTC cells proliferation and apoptosis via miR-455-5p/CXCL12 axis. a Relative circPVT1 level in MTC cells transfected circPVT1 overexpressing vector. b & c The number of colonies formed in MTC cells transfected with circPVT1 overexpressing vector or miR-455-5p mimics or treated with CXCR4 antagonist AMD3100. d Flow cytometry analysis of the number of transfected cells in G1, S, and G2 phases. e Flow cytometry analysis of cell apoptosis in MTC cells transfected with circPVT1 overexpressing vector or miR-455-5p mimics or treated with CXCR4 antagonist AMD3100. * P < 0.05; ** P < 0.01; *** P < 0.001