Fig. 8

Knockdown of circPVT1 and overexpression of miR-455-5p repressed MTC tumor growth and lung metastasis in vivo. a Representative tumor images in each group of mice. b The tumor volume in each group of mice with time. c The tumor weight in each group of mice. d & e CXCL12 and EMT-related protein levels in the tumors from each group of mice. f Representative images of the lung tissues from each group of mice. g Relative numbers of tumor nodules in the lung from each group of mice. h Representative H&E staining images of the lung from each group of mice. * P < 0.05; ** P < 0.01; *** P < 0.001