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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: RETRACTED ARTICLE: Exosomal DLX6-AS1 from hepatocellular carcinoma cells induces M2 macrophage polarization to promote migration and invasion in hepatocellular carcinoma through microRNA-15a-5p/CXCL17 axis

Fig. 1

HCC-exo induce macrophage M2 polarization. a. Electron microscope observation of the morphology of SMMC-7721 cells-derived exosomes; b. Western blot analysis of antigens (CD63, Alix and TSG101) in SMMC-7721 cells-derived exosomes; c. Microscopic observation of THP1 cells before and after PMA induction; d. PKH26 labeling of exosomes; e. RT-qPCR detection of M2 macrophages markers (CD206, CD163, CCL17 and CCL18) after co-culture with HCC-exo; f. RT-qPCR detection of M1 macrophages markers (TNF-α, IL-6 and TGF-β) after co-culture with HCC-exo; data were expressed as mean ± standard deviation (repetition = 3) and evaluated by One-way AVONA and Tukey’s test. & P < 0.05 compared with the PBS group

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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