Fig. 1

CD151 expression is up-regulated in NSCLC tissues and cell lines. a NSCLC samples were immunostained with anti-CD151antibody. Representative adenocarcinomas sample (a–c) and squamous cell carcinomas sample (d–f) are shown. b Effect of the CD151 expression level on overall survival in 150 lung cancer patients was analyzed. c-d Kaplan-Meier analysis of overall survival for CD151 expression in adenocarcinomas or squamous cell carcinomas samples. e CD151 mRNA and protein expression in human NSCLC cell lines were analyzed by RT-PCR and Western blot, respectively. f CD151 mRNA levels in 107 NSCLC tissues and paired noncancerous lung tissues. Bars represent mean ± SEM from three independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001