Fig. 8

Clinical relationship between USP1 and RPS16. a and b Expressions of USP1 and RPS16 at mRNA level in HCC in comparison with normal tissues from the TCGA database. c Kaplan-Meier curves from patients with HCC expressing low and high USP1 from the TCGA database. d Immunohistochemistry assay was performed in HCC and normal adjacent tissue microarray (n = 90). Representative images of USP1 and RPS16 are shown. e Quantification of the USP1 and RPS16 expression in tissues. f The correlation of USP1 and RPS16 protein levels in human HCC. g Kaplan-Meier curves from patients with HCC expressing low and high USP1/RPS16 from the tissue microarray. h Graphical summary of USP1-regulated proliferation and metastasis of HCC