Fig. 1
POSTN is correlated to molecular phenotype of liver cancer stem cell. a-b POSTN mRNA expression was positively correlated with the most common transcriptional regulators in liver cancer stem cells such as ZEB1, TWIST1, GLI1, GLI2, GLI3, RUNX1 (a TCGA database, b ICGC database). c Positive expression of POSTN protein in liver cancer tumor tissues were consistent with the expression of stem cell marker CD133, CD90, CK19, TWIST, CXCR4 and αSMA. d The expression of POSTN mRNA was also positively correlated with these six genes by using GSE1898 subset. e The expression of CD133 mRNA in POSTNHigh HCC tissues was significantly higher than that in POSTNLow HCC tissues. f POSTN (Green) could be co-expressed with CD133 (Red) in liver cancer tissues of POSTN-highly-expressing HCC by using immunofluorescence staining, CD133 was negative expression in POSTN-lowly-expressing HCC tissue. Scale bar, 50 μm