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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: C4b-binding protein α-chain enhances antitumor immunity by facilitating the accumulation of tumor-infiltrating lymphocytes in the tumor microenvironment in pancreatic cancer

Fig. 4

Enhanced apoptotic cell death in the combination of gemcitabine with C4BPA stimulation in human PDAC cells. PANC-1 (upper panels) and Capan-2 (lower panels) cells were treated with control, Gem, or Gem+rhC4BPA for the apoptosis assay. a Analysis of apoptosis by flow cytometry was assessed by Annexin V/PI double-staining. b Comparative analysis of subpopulation of apoptotic cells in PDAC cells treated with control, Gem, or Gem+rhC4BPA. Red or blue box/column indicates early apoptotic cells or late apoptotic/necrotic cells, respectively. Experiments were performed three times independently. Error bars represent the SD. ns, not significant.

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