Fig. 1

The combination of REG and aPD1 results in additive suppression of subcutaneous MC38 tumor growth. a Study design. b Tumor growth curves with mean tumor volumes ± SD (n = 10). c Intratumoral levels of IFNγ mRNA at study end determined by qRT-PCR. d Intratumoral levels of IFNγ protein from total tumor lysates at study end determined by enzyme-linked immunosorbent assay. Mean ± SD (n = 5) and individual values (dots) are shown. *p < 0.05; **p < 0.01; ***p < 0.001