Fig. 4

MiR-600 abrogates the proliferation promoting effect by circRHOBTB3 in PANC-1 cell line. a The efficiency of miR-600 mimics and inhibitor were examined by qRT-PCR in PANC-1 cell lines. b-d The CCK-8 assays, colony formation assays showed and Edu incorporation assays revealed that miR-600 inhibitor reversed the reduced effect of PANC-1 cell proliferation by circRHOBTB3 knockdown. The EdU samples were imaged at 200× magnification. Scale bar = 50 μm. All data are presented as the means ± SD of three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001