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Table 2 Correlation between MYSM1 expression and clinicopathological features of CRC patients in the tissue microarray of survival

From: MYSM1 inhibits human colorectal cancer tumorigenesis by activating miR-200 family members/CDH1 and blocking PI3K/AKT signaling

  Total Low MYSM1 High MYSM1   
Variable N % N % N % χ2 P Valuea
Survival
 Alive 40 40.0 11 18.0 29 74.4 31.449 < 0.001
 Deceased 60 60.0 50 82.0 10 25.6  
Pathological Diagnosis
 Adjacent Normal Tissue 80 44.4 5 7.6 75 65.8 57.370 < 0.001
 Carcinoma 100 55.6 61 92.4 39 34.2  
Histologic Subtypes
 Adenocarcinoma 44 44.4 25 41.0 19 50.0 7.549 0.023
 Tubular Adenocarcinoma 40 40.4 22 36.1 18 47.4  
 Mucinous Adenocarcinoma 15 15.2 14 22.9 1 2.6  
Location
 Ascending Colon 33 33.7 23 38.3 10 26.3 5.706 0.127
 Transverse Colon 26 26.5 18 30.0 8 21.1  
 Descending Colon 11 11.2 7 11.7 4 10.5  
 Rectosigmoid Colon 28 28.6 12 20.0 16 42.1  
Age (y)
  ≤ 60 21 22.3 11 18.6 10 28.6 2.040 0.361
 60–80 57 60.7 39 66.1 18 51.4  
  ≥ 80 16 17.0 9 15.3 7 20.0  
Gender
 M 54 54.5 35 58.3 19 48.7 0.881 0.348
 F 45 45.5 25 41.7 20 51.3  
Grade
  < II 7 7.0 4 6.5 3 7.7 2.679 0.262
  < III 78 78.0 45 73.8 33 84.6  
  ≥ III 15 15.0 12 19.7 3 7.7  
Stage
 1 6 6.1 1 1.7 5 13.2 7.902 0.048
 2 54 55.1 31 51.7 23 60.5  
 3 35 35.7 26 43.3 9 23.7  
 4 3 3.1 2 3.3 1 2.6  
Tumor Stage
  ≤ T2 7 7.3 2 3.4 5 13.5 6.741 0.034
 T3 75 78.1 45 76.3 30 81.1  
 T4 14 14.6 12 20.3 2 5.4  
Nodal Stage
 N0 60 61.2 32 53.3 28 73.7 5.994 0.050
 N1 27 27.6 18 30.0 9 23.7  
 N2 11 11.2 10 16.7 1 2.6  
Metastasis
 M0 97 97.0 59 96.7 38 97.4 0.042 0.838
 M1 3 3.0 2 3.3 1 2.6  
  1. aThe P values were calculated in SPSS 25.0 using a chi-square test
  2. P values < 0.05 were considered to indicate statistical significance