Journal of Experimental & Clinical Cancer Research

Table 2 Correlation between MYSM1 expression and clinicopathological features of CRC patients in the tissue microarray of survival

From: MYSM1 inhibits human colorectal cancer tumorigenesis by activating miR-200 family members/CDH1 and blocking PI3K/AKT signaling

	Total		Low MYSM1		High MYSM1
Variable	N	%	N	%	N	%	χ²	P Value^a
Survival
Alive	40	40.0	11	18.0	29	74.4	31.449	< 0.001
Deceased	60	60.0	50	82.0	10	25.6		< 0.001
Pathological Diagnosis
Adjacent Normal Tissue	80	44.4	5	7.6	75	65.8	57.370	< 0.001
Carcinoma	100	55.6	61	92.4	39	34.2		< 0.001
Histologic Subtypes
Adenocarcinoma	44	44.4	25	41.0	19	50.0	7.549	0.023
Tubular Adenocarcinoma	40	40.4	22	36.1	18	47.4
Mucinous Adenocarcinoma	15	15.2	14	22.9	1	2.6
Location
Ascending Colon	33	33.7	23	38.3	10	26.3	5.706	0.127
Transverse Colon	26	26.5	18	30.0	8	21.1
Descending Colon	11	11.2	7	11.7	4	10.5
Rectosigmoid Colon	28	28.6	12	20.0	16	42.1
Age (y)
≤ 60	21	22.3	11	18.6	10	28.6	2.040	0.361
60–80	57	60.7	39	66.1	18	51.4
≥ 80	16	17.0	9	15.3	7	20.0
Gender
M	54	54.5	35	58.3	19	48.7	0.881	0.348
F	45	45.5	25	41.7	20	51.3		0.348
Grade
< II	7	7.0	4	6.5	3	7.7	2.679	0.262
< III	78	78.0	45	73.8	33	84.6
≥ III	15	15.0	12	19.7	3	7.7
Stage
1	6	6.1	1	1.7	5	13.2	7.902	0.048
2	54	55.1	31	51.7	23	60.5
3	35	35.7	26	43.3	9	23.7
4	3	3.1	2	3.3	1	2.6
Tumor Stage
≤ T₂	7	7.3	2	3.4	5	13.5	6.741	0.034
T₃	75	78.1	45	76.3	30	81.1
T₄	14	14.6	12	20.3	2	5.4
Nodal Stage
N₀	60	61.2	32	53.3	28	73.7	5.994	0.050
N₁	27	27.6	18	30.0	9	23.7
N₂	11	11.2	10	16.7	1	2.6
Metastasis
M₀	97	97.0	59	96.7	38	97.4	0.042	0.838
M₁	3	3.0	2	3.3	1	2.6		0.838

^aThe P values were calculated in SPSS 25.0 using a chi-square test
P values < 0.05 were considered to indicate statistical significance

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ISSN: 1756-9966

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