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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Therapeutic inhibition of GAS6-AS1/YBX1/MYC axis suppresses cell propagation and disease progression of acute myeloid leukemia

Fig. 3

GAS6-AS1 enhances proliferation of leukemia cells by inducing G1-S cell cycle transition and reducing apoptosis. A, B, C The bar chart represented the percentage of U937, HL-60 and Kasumi-1 cells in G0/G1, S or G2/M phase, following transfection-mediated GAS6-AS1 knockdown or overexpression. D, E Flow cytometry detecting the apoptotic rates of U937, HL-60 and Kasumi-1 cells after GAS6-AS1 knockdown or overexpression. LR, early apoptotic cells; UR, terminal apoptotic cells. Data were depicted as mean ± s.e.m., *P < 0.05

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