Fig. 8From: Circ_0000658 knockdown inhibits epithelial-mesenchymal transition in bladder cancer via miR-498-induced HMGA2 downregulationThe mechanism graph of the regulatory network and function of circ_0000658 in BCa. Circ_0000658 competitively binds to miR-498 and downregulates miR-498 expression, thus upregulating HMGA2. By this mechanism, circ_0000658 stimulates EMT, proliferation, invasion and migration of BCa cells and promotes the ensuing BCa progressionBack to article page