Fig. 4

Overview of ongoing and completed clinical trials with CD70-targeting agents. Completed trials (solid line) and ongoing trials (dashed line) were sorted based on study start date. Antibody-drug conjugates (ADC, blue); Antibody (Ab, Red); Chimeric antigen receptor (CAR, Green). Efficacy data are depicted when available. Abbreviations: ADC, antibody drug conjugate: Ab, antibody; CAR, chimeric antigen receptor; CR, complete remission; PR, partial remission; SD, stable disease; CRi, CR with incomplete hematological recovery; NHL, non-Hodgkin lymphoma; CTCL, cutaneous T cell lymphoma; RCC, renal cell carcinoma; NPC, nasopharynx carcinoma; AML, acute myeloid leukemia; MDS, myelodysplastic syndrome; BCL, B cell lymphoma; MM, multiple myeloma; TCL, T cell lymphoma; Pt, patients; Exp, expected