Fig. 2

The effects of CM from M1-like TAMs on the malignant behaviors of OSCC cells. A-D. The effect of CM on the colony formation (A), invasion (B), migration (C), and microsphere forming (D) potential of OSCC cells; Data were represented as the mean ± SD of three independent experiments, **p<0.01. E-F. The effects of CM from M1-like TAMs on the malignant behaviors of OSCC cells in vivo. Mice with OSCC xenografts were received intraperitoneal injection of 1ml CM from M1-like TAMs or from M0 5 days per week, respectively. E. Representative images for SCC25 xenografts, and tumor volume and tumor weight were compared; F. Representative images for Cal27 xenografts, and tumor volume and tumor weight were compared, **p<0.01