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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: MiR-423-5p prevents MALAT1-mediated proliferation and metastasis in prostate cancer

Fig. 6

In vivo effect of MiR-423-5p mimic expression on survival and metastasis. A Graphs representing tumours’ formation and growth vs. time (Days) in PC3 control and MiR-423-5p mimic expressing cells that were xenografted NOD/SCID mice, respectively. B Kaplan-Mayer graph representing the percentage of survival NOD/SCID mice carrying PC3 cells xenografted control and MiR-423-5p mimic expressing tumours. C Representative images of metastases in the control and MiR-423-5p mimic groups (images from only one experiment shown, left panel). D Quantification of the number of metastasis is shown on the right panel graph (Total number of mice in each group = 12 from two independent experiments). **P = 0.0051. E Graphs representing the relative MALAT-1 and MiR-423-5p expression in the tumor tissue from control and MiR-423-5p mimic groups (*p < 0.05)

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