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Table 2 Correlation of clinic-pathological features with MALAT1 expression in PCa TMA corhort

From: MiR-423-5p prevents MALAT1-mediated proliferation and metastasis in prostate cancer

 

Cases

Negative

Low Positive

High Positive

pValue (X2)

(Tot 71)

Normal

8–11.3%

7–87.5%

1–12.5%

0–0%

0.001

Cancer

63–88.7%

12–19%

37–58.7%

14–22.2%

T1-T2

30–47.6%

6–20%

23–76.7%

1–3.3%

0.006

T3-T4

33–52.4%

6–18.2%

14–42.4%

13–39.4%

N0

51–80.9%

11–21.6%

34–66.7%

6–11.7%

0.001

N1

12–19.1%

1–8.3%

3–25%

8–66.7%

M0

55–87.3

11–20%

35–63.7%

9–16.3%

0.001

M1

8–12.7%

1–12.5%

2–25%

5–62.5%

Stage 1-2

30–47.6%

6–20%

23–76.7%

1–3.3%

0.001

Stage 3-4

33–52.4%

6–18.2%

14–42.4%

13–39.4%

WHO Grade 1-2

24–38.1%

6–25%

17–70.8%

1–4.2%

0.001

WHO Grade 3-4

37–58.7%

5–13.5%

19–51.4%

13–35.1%

  1. Spearman’s Rho bivariate analysis correlationcoefficient indicates a positive correlation between Malat1 histopathological score and patient’s clinical parameters analyzed. Correlations are significant at the 0.01 and 0.05 levels (2-tailed). The X squared tests of contingency performed between the same factors is significant with a p-value < 0.01. Frequency tables and all the statistical analyses were performed using IBM SPSS Ver. 25