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Table 2 Univariate and multivariate analyses for predictors of overall survival

From: Macrophages-aPKCɩ-CCL5 Feedback Loop Modulates the Progression and Chemoresistance in Cholangiocarcinoma

Vriables

Overall survival

Univariate analysis

Multivariate analysis

HR

95%CI

P value

HR

95%CI

P value

Age (<60 vs ≥60)

1.574

0.779-3.178

0.206

   

Gender (male vs female)

0.731

0.371-1.440

0.365

   

Lymph node metastasis (no vs yes)

5.004

2.258-11.087

<0.001

10.933

4.133-14.481

0.027

TNM stage (I/II vs III/IV)

3.812

1.783-8.147

0.001

   

Differentiation (well vs moderate/poor)

7.726

2.644-22.582

<0.001

8.368

2.403-29.145

0.001

aPKCɩ expression (low vs high)

4.329

2.000-9.368

<0.001

4.766

1.549-14.661

0.006

CD68 expression (low vs high)

2.529

1.094-5.844

0.030

   

CD80 expression (low vs high)

1.272

0.646-2.503

0.486

   

CD206 expression (low vs high)

5.981

2.567-13.936

<0.001

3.526

1.268-9.808

0.016

  1. HR hazard ratio, CI confidence interval