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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: TRPM7 silencing modulates glucose metabolic reprogramming to inhibit the growth of ovarian cancer by enhancing AMPK activation to promote HIF-1α degradation

Fig. 6

Altered AMPK activation or HIF-1α expression modulates the TRPM7 silencing-decreased expression of glycolysis-relative regulators and increased expression of OXPHOS-relative regulators in ovarian cancer cells. A-D Western blot analysis of IDH3B, UQCRC1, HIF-1α, HK2, PDK1 expression and AMPK phosphorylation in the indicated groups of cells

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