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Table 2 Correlation between APOE expression and clinicopathological features in patients with PTC (n = 100)

From: FTO suppresses glycolysis and growth of papillary thyroid cancer via decreasing stability of APOE mRNA in an N6-methyladenosine-dependent manner

Characteristic

n

APOE

P value

High expression (%)

Low expression (%)

Gender

 Male

33

18 (54.5)

15 (45.5)

0.619

 Female

67

33 (49.3)

34 (50.7)

 

Age (Years)

  < 55

41

19 (46.3)

22 (53.7)

0.437

  ≥ 55

59

32 (54.2)

27 (45.8)

 

Tumor size (cm)

  < 2

47

17 (36.2)

30 (63.8)

0.005*

  ≥ 2

53

34 (64.2)

19 (35.8)

 

Extrathyroidal invasion

 Yes

33

22 (66.7)

11 (33.3)

0.028*

 No

67

29 (43.3)

38 (56.7)

 

Lymph node metastasis

 Yes

72

40 (55.6)

32 (44.4)

0.144

 No

28

11 (39.3)

17 (60.7)

 

TNM stage

 I-II

85

43 (50.6)

42 (49.4)

0.854

 III-IV

15

8 (53.3)

7 (46.7)

 
  1. *p < 0.05