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Table 2 Ranking using Random Forest Classifier (RFC) of DEGs identified by Wilcoxon test

From: Identification of a novel gene signature predicting response to first-line chemotherapy in BRCA wild-type high-grade serous ovarian cancer patients

Gene symbol

MDA

MDG

MDA (%)

MDG (%)

Mean Percent

Wilcoxon P-value

Estimated shift

95% Conf. Interval

GNG11

20.13

2.25

96.49

100.00

98.25

0.0048

−1.09

−1.71, −0.34

SLC15A3

20.70

1.55

100.00

48.86

74.43

0.0293

−0.98

−1.75, − 0.17

PLCG2

20.24

1.57

97.16

50.18

73.67

0.0259

−0.91

−1.70, − 0.13

IGFBP7

13.04

1.50

52.42

45.17

48.80

0.0284

−0.42

− 0.89, − 0.06

CKB

12.57

1.46

49.47

41.73

45.60

0.0404

0.94

0.05, 1.79

RNF24

8.81

1.61

26.12

53.02

39.57

0.0050

0.59

0.20, 1.12

CTNNBL1

9.07

1.47

27.75

43.11

35.43

0.0178

0.53

0.05, 1.03

UQCC1

9.65

1.41

31.33

38.07

34.70

0.0101

0.54

0.15, 0.93

TSPAN31

4.60

1.51

0.00

45.95

22.97

0.0404

0.53

0.03, 0.98

TTI1

5.72

0.89

6.94

0.00

3.47

0.0275

0.59

0.06, 1.21

  1. DEGs Differentially expressed genes, MDA Mean Decrease Accuracy, MDG Mean Decrease Gini impurity