Fig. 10

The EMILIN-2 levels correlate with the monocyte/lymphocyte ratio. A Stratification of the CRC patients cohort examined in our Institute based on the EMILIN-2 levels; the clinical parameters available for 11 patients are indicated. pCR: pathological complete response; TRG: tumor regression grade; MLR: monocyte/lymphocyte ratio. B Correlation matrix showing the association between the immune circulating cells and the EMILIN-2 levels in the patient cohort reported in A. Positive correlations are highlighted in blue and negative in red, color intensity and size of the circles being proportional to the correlation coefficients; MLR: monocyte/lymphocyte ratio. C Pearson correlation analyses of the levels of EMILIN-2 and the number of circulating monocytes (left) and the monocyte/lymphocyte ratio (MLR, right) in the patient cohort reported in A. D Levels of EMILIN-2 in CRC patients following stratification based on the monocyte/lymphocyte ratio (MLR) value (threshold = 0.355)