Fig. 10
From: Tumor-associated macrophages in cancer: recent advancements in cancer nanoimmunotherapies
A Scheme 1 a Preparation of M1/SLNP. b Schematic illustration of M1/SLNP for tumor targeting delivery to enhance the therapeutic efficiency of HCC, in which dual functional M1-type macrophages as targeting delivery vessel and therapeutic tool. (B-H) M1/SLNP enhanced antitumor efficacy in vitro and in vivo. B Cell viability of M1/SLNP in Hepa1–6 cells in vitro. C in vivo tumor volume changes. D Photographs of tumors. E Tumor weights (F) Body weight changes from Hepa1–6-bearing mice treated with NS, M, M1, free SF, SLNP, M/SLNP, and M1/SLNP via the tail vein. H H&E and Ki67 results of tumor tissues. Magnification: H&E 200×, Ki67 200×. +++p [158].