Dynamic liquid biopsy components as predictive and prognostic biomarkers in colorectal cancer

Table 3 Expression of circulating miRNAs in CRC

miRNAs	Expression in CRC	Biomarker	Sample type	Ref
miR-21	Upregulated	Diagnostic	Plasma, Saliva	[105]
miR-30e-3p, let-7d-5p, let-7a-5p, let-7f-5p miR-375, miR-486-3p, miR-486-5p, miR-1180-3p	Upregulated Downregulated	Diagnostic	Serum	[106]
miR-92a-3p	Upregulated	Diagnostic	Plasma, Serum	[107]
miR-762	Upregulated	Diagnostic	Serum	[53]
miR-211, miR-25	Upregulated	Diagnostic	Plasma	[54]
miR-618	Upregulated	Prognostic	Serum	[108]
miR-21, miR-145, miR-203, miR-155, miR-210, miR-31, miR-345	Upregulated	Diagnostic	Plasma	[109]
miR-28-3p, let-7e-5p, miR-106a-5p, miR-542-5p	Upregulated	Diagnostic	Plasma	[55]
miR-449a	Downregulated	Diagnostic, Prognostic	Plasma	[110]
miR-29c, miR-149	Downregulated	Diagnostic	Serum	[111]
miRNA-223	Upregulated	Diagnostic	Serum	[112]
miR-19a-3p, miR-203-3p, miR-221-3p, and let-7f-5p	Upregulated	Diagnostic	Serum	[113]
miR-30e-3p, miR-146a-5p miR-148a-3p	Upregulated Downregulated	Diagnostic	Serum	[114]
miR-451a	Upregulated	Diagnostic	Serum	[115]
miR-21, miR-23a, miR-27a	Upregulated	Diagnostic	Serum	[116]
miR-584-5p, miR-15b-5p, miR-425-3p	Upregulated	Diagnostic	Plasma	[117]
miR-944	Downregulated	Diagnostic	Serum	[118]
miR-21, miR-92a	Upregulated	Diagnostic	Plasma	[119]
miR-592	Upregulated	Diagnostic	Serum	[120]

ISSN: 1756-9966