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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Targeting selenoprotein H in the nucleolus suppresses tumors and metastases by Isovalerylspiramycin I

Fig. 1

Genetic organization of the Carrimycin biosynthetic gene cluster and main steps of ISP I biosynthesis. A The chemical structure of Carrimycin and its main components: ISP I, II and III. B Genetic organization of the isovalerylspiramycin biosynthetic gene cluster. The proposed functions of the gene products in isovalerylspiramycin biosynthesis are indicated by various filling patterns. C Proposed pathway for ISP I biosynthesis. bsm44 is 4″-O-isovaleryltransferase gene (ist) responsible for the formation of isovaleryl group at 4″ position. The bsm4 is 3-O-acyltransferase gene involved in the acylation at 3″ position

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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