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Fig. 4 | Journal of Experimental & Clinical Cancer Research

Fig. 4

From: The MYCN inhibitor BGA002 restores the retinoic acid response leading to differentiation or apoptosis by the mTOR block in MYCN-amplified neuroblastoma

Fig. 4

BGA002-RA treatment affects the migration capacity of MNA-NB. A optical microscopy image of the Kelly cell line treated at time zero (above the line) or after 72 hours (below the line). Exemplary images from 1 out of 3 experiments. The scratched zone is highlighted with yellow contouring. B bar plot represents wound-healing closure normalized over the control after 72 hours for 4 different MNA-NB cell lines (n = 3 different biological replicates). The middle line is the mean and the whiskers are the standard deviation. CTRL, control. Where indicated in the figure: *, p < 0.05; **, p < 0.01; ***, p < 0.001; ****, p < 0.0001

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