Fig. 8

Knockdown of KIF23 inhibits TNBC progression in vivo by targeting Wnt/β-catenin signaling pathway. A-F Representative images of xenograft tumors, tumor sizes and weights of KIF23 knockdown (sh-KIF23) and control (sh-NC) group. G-H Ki-67 expression was analyzed by IHC and lung metastasis nodes were analyzed by H&E. I-J Western blot was used to determine the protein expression of genes that related to the pathways after transfecting with si-FOXM1 and protein expression level of these genes was detected after the restoration of KIF23. Data were shown as mean ± SD, *p <0.05, **p <0.01, ***p<0.001