Fig. 1

Elevated B3GNT5 expression was tightly associated with BLBC. (A) Box-plots indicated B3GNT5 mRNA expression in four different subtypes of breast cancer from four datasets (TCGA, NKI295, GSE1456 and GSE21653). (B) Box-plots indicated B3GNT5 mRNA expression in BLBC and luminal cell lines from different datasets (GSE12777, GSE16732, GSE10890, E-TAMB-181 and CCLE). Comparisons are made using the two-tailed Student’s t-test. (C) Expression of B3GNT5 mRNA was analyzed by quantitative real-time PCR in breast cancer cell lines (left panel), and the right panel showed the comparison analysis between basal-like and luminal breast cancer cell lines from left panel. Data are shown as mean ± SD based on three independent experiments. (D) Expression of B3GNT5 mRNA was analyzed by quantitative real-time PCR in clinical breast cancer samples. Data are shown as mean ± SD based on three independent experiments