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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming

Fig. 2

Most relevant proteins and metabolites differentially represented in bile from control and CCA bearing rats. a Identity of proteins showing significantly increased concentrations (Fold change > 0.9) in bile from TAA-treated rats vs controls (Vehicle). The expression of the corresponding genes as reported in the TCGA database is shown. AC: accession number. b Metabolites showing significantly altered concentrations in bile from TAA-treated rats vs controls (Vehicle). *p < 0.05, **p < 0.01, ***p < 0.001

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