Fig. 7

A Heatmaps generated from ChIP-Seq data analyses showed the occupancy of LYL1 in NB4, HL-60, and Kasumi-1 cell lines. B distribution of LYL1 binding to genomic regions in the human AML cell line NB4, HL-60, and Kasumi-1 as assessed by ChIP-Seq. Peak annotation of LYL1 is summarized in a pie chart format. C Motif enrichment analysis of the 5264 specific LYL1 peaks in NB4 cells. D Venn diagram of common genes bound by LYL1 at its promoter regions in AML cell line NB4, HL-60, and Kasumi-1. E qRT-PCR results of 11 genes in NB4 cell line when silencing LYL1