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Table 1 The correlations between AGK expression and the clinicopathological features of the patients with epithelial ovarian cancer

From: Acylglycerol kinase promotes ovarian cancer progression and regulates mitochondria function by interacting with ribosomal protein L39

Characteristics

Number of cases (%)

AGK expression (%)

P value

Low or no expression

High expression

Age (years)

   

0.710

 <45

49 (35)

18 (36.7)

31 (63.2)

 

  ≥ 45

91 (65)

30 (33.0)

61 (67.0)

 

CA125 level

   

0.482

 <500 U/ml

67 (47.9)

25 (37.3)

42 (62.7)

 

  ≥ 500 U/ml

73 (52.1)

23 (31.5)

50 (68.5)

 

Tumor size

   

0.206

 <10 cm

58 (41.4)

16 (27.6)

42 (72.4)

 

  ≥ 10 cm

82 (58.6)

32 (39.0)

50 (61.0)

 

The volume of ascites

   

0.001

 <1000 ml

100 (71.4)

43 (43.0)

57 (57.0)

 

  ≥ 1000 ml

40 (28.6)

5 (12.5)

35 (87.5)

 

Peritoneal cytology

   

0.004

 Positive

68 (48.6)

15 (22.0)

53 (78.0)

 

 Negative

72 (51.4)

33 (45.8)

39 (54.2)

 

Pathological type

   

0.238

 Serous

80 (57.1)

25 (31.2)

55 (68.8)

 

 Mucinous

14 (10.0)

8 (57.1)

6 (42.9)

 

 Poorly differentiated

36 (25.7)

12 (33.3)

24 (66.7)

 

 Othersa

10 (7.1)

3 (30.0)

7 (70.0)

 

Grade of differentiation

   

0.376

 G1

59 (42.1)

23 (39.0)

36 (61.0)

 

 G2

46 (32.9)

14 (30.4)

32 (69.6)

 

 G3

18 (12.9)

6 (33.3)

12 (66.7)

 

 Unknown

17 (12.1)

5 (29.4)

12 (70.6)

 

FIGO stage

   

0.002

 I

30 (21.4)

18 (60.0)

12 (30.0)

 

 II+ III + IV

110 (78.6)

32 (29.1)

80 (70.9)

 

Lymph node metastasis

   

0.688

 Positive

21 (15.0)

8 (38.1)

13 (61.9)

 

 Negative

23 (16.4)

7 (30.4)

16 (69.6)

 

 Not do RPLNDb

96 (68.6)

33 (34.4)

63 (65.6)

 

Cytoreductive surgeryc

   

0.812

 Optimal

107 (76.4)

35 (32.7)

72 (67.3)

 

 Suboptimal

33 (23.6)

13 (39.4)

20 (60.6)

 
  1. aEndometrioid adenocarcinoma 2 cases, clear cell carcinoma 3 cases, mixed epithelial carcinoma 5 cases
  2. bRPLND, retroperitoneal lymph node dissection, including unilateral or bilateral pelvic lymphadenectomy and /or paraortic lymphadenectomy
  3. cCytoreductive surgery: Optimal, the diameter of biggest residual lesions < 2 cm;Suboptimal, the diameter of biggest residual lesions ≥2 cm
  4. P < 0.05 was considered statistically significant