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Table 1 The correlations between AGK expression and the clinicopathological features of the patients with epithelial ovarian cancer

From: Acylglycerol kinase promotes ovarian cancer progression and regulates mitochondria function by interacting with ribosomal protein L39

Characteristics Number of cases (%) AGK expression (%) P value
Low or no expression High expression
Age (years)     0.710
 <45 49 (35) 18 (36.7) 31 (63.2)  
  ≥ 45 91 (65) 30 (33.0) 61 (67.0)  
CA125 level     0.482
 <500 U/ml 67 (47.9) 25 (37.3) 42 (62.7)  
  ≥ 500 U/ml 73 (52.1) 23 (31.5) 50 (68.5)  
Tumor size     0.206
 <10 cm 58 (41.4) 16 (27.6) 42 (72.4)  
  ≥ 10 cm 82 (58.6) 32 (39.0) 50 (61.0)  
The volume of ascites     0.001
 <1000 ml 100 (71.4) 43 (43.0) 57 (57.0)  
  ≥ 1000 ml 40 (28.6) 5 (12.5) 35 (87.5)  
Peritoneal cytology     0.004
 Positive 68 (48.6) 15 (22.0) 53 (78.0)  
 Negative 72 (51.4) 33 (45.8) 39 (54.2)  
Pathological type     0.238
 Serous 80 (57.1) 25 (31.2) 55 (68.8)  
 Mucinous 14 (10.0) 8 (57.1) 6 (42.9)  
 Poorly differentiated 36 (25.7) 12 (33.3) 24 (66.7)  
 Othersa 10 (7.1) 3 (30.0) 7 (70.0)  
Grade of differentiation     0.376
 G1 59 (42.1) 23 (39.0) 36 (61.0)  
 G2 46 (32.9) 14 (30.4) 32 (69.6)  
 G3 18 (12.9) 6 (33.3) 12 (66.7)  
 Unknown 17 (12.1) 5 (29.4) 12 (70.6)  
FIGO stage     0.002
 I 30 (21.4) 18 (60.0) 12 (30.0)  
 II+ III + IV 110 (78.6) 32 (29.1) 80 (70.9)  
Lymph node metastasis     0.688
 Positive 21 (15.0) 8 (38.1) 13 (61.9)  
 Negative 23 (16.4) 7 (30.4) 16 (69.6)  
 Not do RPLNDb 96 (68.6) 33 (34.4) 63 (65.6)  
Cytoreductive surgeryc     0.812
 Optimal 107 (76.4) 35 (32.7) 72 (67.3)  
 Suboptimal 33 (23.6) 13 (39.4) 20 (60.6)  
  1. aEndometrioid adenocarcinoma 2 cases, clear cell carcinoma 3 cases, mixed epithelial carcinoma 5 cases
  2. bRPLND, retroperitoneal lymph node dissection, including unilateral or bilateral pelvic lymphadenectomy and /or paraortic lymphadenectomy
  3. cCytoreductive surgery: Optimal, the diameter of biggest residual lesions < 2 cm;Suboptimal, the diameter of biggest residual lesions ≥2 cm
  4. P < 0.05 was considered statistically significant