Table 1 FAT1 gene status in various HNSCC cell lines

BHY

Nonsense_Mutation

SNP

OC

Alveolus

Negative

M

Negative

BICR 18

Silent

SNP

LX

Larynx

Positive

M

N/A

Frame_Shift_Del

DEL

-

-

-

-

-

Frame_Shift_Ins

INS

-

-

-

-

-

BICR 31

Nonsense_Mutation

SNP

OC

Tongue

Positive

M

N/A

BICR 56

Nonsense_Mutation

SNP

OC

Tongue

Positive

F

N/A

BICR78

Splice_Site

SNP

OC

Oral alveolus

N/A

M

N/A

CAL-33

Nonsense_Mutation

SNP

OC

Tongue

Negative

M

Negative

FaDu

Frame_Shift_Del

DEL

OC

Hypopharynx

Positive

M

Negative

H357

Frame_Shift_Del

DEL

OC

Tongue

N/A

M

N/A

Nonsense_Mutation

SNP

-

-

-

-

-

H376

Missense_Mutation

SNP

OC

Floor of mouth

N/A

F

N/A

HO1N1

Nonsense_Mutation

SNP

OC

Baccul Muc

N/A

N/A

N/A

HO1U1

Nonsense_Mutation

SNP

OC

Mouth Floor

N/A

N/A

N/A

HSC-2

Missense_Mutation

SNP

OC

Floor of mouth

Negative

M

N/A

HSC-3

Frame_Shift_Del

DEL

OC

Tongue

Positive

M

Negative

JHU022

Missense_Mutation

SNP

LX

Larynx

Positive

M

Negative

MDA686TU^a

Missense_Mutation

SNP

OP

Base of Tongue

Positive

M

Negative

OSC19

Frame_Shift_Del

DEL

OC

Tongue

Positive

M

N/A

PE/CA-PJ41

Missense_Mutation

SNP

OC

N/A

N/A

F

N/A

PE/CA-PJ49

Nonsense_Mutation

SNP

OC

Tongue

M

N/A

Missense_Mutation

SNP

-

-

-

-

-

SCC-15

Missense_Mutation

SNP

OC

Tongue

N/A

M

Negative

SNU-46

Frame_Shift_Del

DEL

LX

Larynx

N/A

M

Negative

SNU-1041

Missense_Mutation

SNP

OC

Pharynx

N/A

N/A

N/A

Nonsense_Mutation

SNP

-

-

-

-

-

SqCCY1^a

Frame-Shift-Ins

INS

OC

N/A

N/A

M

Negative

UMSCC1^a

Missense_Mutation

SNP

OC

Floor of mouth

Negative

M

Negative

UMSCC9

Missense_Mutation

SNP

OC

Tongue

Negative

F

Negative

UMSCC11A

Missense_Mutation

SNP

OC

Epiglottis

Positive

M

Negative

UMSCC25

Frame-Shift-Del

DEL

LN

Lymph Node

Positive

M

Negative

UMSCC28

Nonsense_Mutation

SNP

-

True cord

Negative

F

Negative

UMSCC41

Missense_Mutation

SNP

-

Arytenoid

Positive

M

Negative

UMSCC74A

Missense_Mutation

SNP

OP

Base of Tongue

Negative

M

Negative

UMSCC74B

Missense_Mutation

SNP

Recurrence

Intraoral

Negative

M

Negative

UMSCC76

Missense_Mutation

SNP

LN

Lymph Node

Positive

M

Negative

UMSCC81B

Missense_Mutation

SNP

-

True cord

Negative

M

Negative

UMSCC104

Missense_Mutation

SNP

OC

Floor of mouth

Positive

M

Positive

UPCISCC116

Frame_Shift_Del

DEL

OC

ALV Ridge

N/A

M

Nagative

YD-10B

Frame_Shift_Del

DEL

OC

Tongue

N/A

M

N/A