Fig. 1

IGF2BP3 promotes the proliferation of GC. A 362 overlapping genes between RBP genes (1542) and differential expression genes of STAD from the TCGA database. B IGF2BP3 mRNA expression between GC tissues and adjacent tissues of STAD in the TCGA database. C IGF2BP3 protein expression in GC tissues. D Association between IGF2BP3 expression and the overall survival in GC patients from the Kaplan–Meier plotter database. E–F CCK-8 assay of SGC7901 and BGC823 cells following IGF2BP3 (E) knockdown or (F) stable overexpression. G Plate colony formation assay of SGC7901 and BGC823 cells following IGF2BP3 knockdown. H EdU assay of SGC7901 and BGC823 cells following IGF2BP3 knockdown. I Plate colony formation assay in SGC7901 and BGC823 cells that stably overexpressed IGF2BP3. J EdU assay in SGC7901 and BGC823 cells stably overexpressing IGF2BP3. The P-values were calculated using the two-tailed Student’s t test. *P < 0.05