Fig. 1

Highly-expressed ETV1 indicates poor prognosis in HCC. (A) The relative ETV1 mRNA level in 10 cases of normal liver specimens, as well as 50 cases of primary HCC specimens and paired paracancerous nontumorous specimens was detected by RT-qPCR (left). ETV1 mRNA levels in 22 cases of primary HCC specimens without recurrence and 28 cases with recurrence (middle). ETV1 mRNA levels in 27 cases of primary HCC specimens without metastasis and 23 cases with metastasis (right). (B) Representative IHC staining (left) and IHC scores (right) of ETV1 in paired primary HCC specimens and nontumorous specimens in two independent HCC cohorts. Scale bars, 200 µm (upper), 50 µm (lower). (C) OS and recurrence rates curves by Kaplan-Meier for HCC tissues with positive and negative ETV1 levels in two independent HCC cohorts. * Represented p < 0.05. All data were displayed as Mean ± SD