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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Heterogeneity of triple negative breast cancer: Current advances in subtyping and treatment implications

Fig. 1

Overview of the characteristic mutation profile, copy number, gene expression and pathway enrichment for the different triple negative breast cancer subtypes Triple negative breast cancer subtypes of luminal androgen receptor (LAR), basal-like immune suppressed (BLIS), basal-like immune activated (BLIA), mesenchymal (MES) and the possible addition of mesenchymal stem-like (MSL) are shown at the core. Genes and pathways denoted in red (indicate high expression) while those denoted in green (indicate low expression). Data are aggregated from Lehmann et al.[57], Burstein et al.[7], Jiang et al.[6], Bareche et al.[35], Bareche et al.[64], Lehmann et al.[58], Gong et al.[76] and Asleh et al.[60]. Abbreviations: TNBC, triple negative breast cancer; HRD,

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